Modulation of age-associated immune dysfunction and allergic responses by Mongolian Lycium ruthenicum extract in murine models

Prolonged intake of Mongolian L. ruthenicum extract suppressed age-associated Th2-skewed allergic inflammation without disturbing immune homeostasis. These findings suggest that sustained LR supplementation may counteract immunosenescence and help maintain immune balance during aging.

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Publication Details

Journal
Journal of Pharmacological Sciences
Published
2026-02-18
DOI
https://doi.org/10.1016/j.jphs.2026.02.004
Primary Topic
Polysaccharides and Plant Cell Walls
Type
article
Field-Weighted Citation Impact
0.00
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article

Modulation of age-associated immune dysfunction and allergic responses by Mongolian Lycium ruthenicum extract in murine models

Ibuki Yasuda, Tomoki Fukuyama, Mao Kaneki, Mana Ichikawa et al.
Journal of Pharmacological Sciences
Polysaccharides and Plant Cell Walls
article

Modulation of age-associated immune dysfunction and allergic responses by Mongolian Lycium ruthenicum extract in murine models

Ibuki Yasuda, Tomoki Fukuyama, Mao Kaneki, Mana Ichikawa, Chiharu Ohira, Naoki Iwashita, Chizuki Usui, Yoshiichi Takagi
article en

Abstract

Prolonged intake of Mongolian L. ruthenicum extract suppressed age-associated Th2-skewed allergic inflammation without disturbing immune homeostasis. These findings suggest that sustained LR supplementation may counteract immunosenescence and help maintain immune balance during aging.

Journal of Pharmacological SciencesVol. 160(4)
Azabu University (JP)
Clean water and sanitation
Openalex Percentile: Top 51%
Polysaccharides and Plant Cell Walls
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