Nervonic acid confers neuroprotection in a zebrafish model of diabetic neuropathy by promoting myelin repair and metabolic modulation

These findings demonstrate that NA confers robust neuroprotection in DN by alleviating inflammation and oxidative stress, preserving neuronal structure and function, and reprogramming key metabolic pathways.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2026-02-18
DOI
https://doi.org/10.3389/fphar.2026.1721486
Primary Topic
Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Nervonic acid confers neuroprotection in a zebrafish model of diabetic neuropathy by promoting myelin repair and metabolic modulation

Shasha Wang, Bingbing Cao, Tao Zhang, Lushan Yu et al.
Frontiers in Pharmacology
Neurological Disorders and Treatments
article

Nervonic acid confers neuroprotection in a zebrafish model of diabetic neuropathy by promoting myelin repair and metabolic modulation

Shasha Wang, Bingbing Cao, Tao Zhang, Lushan Yu, Jie Guo, Qinwen Wang, Yiqiao Xu, Mingzhu Dai, Huan Ge, Ximin Zhu
article en

Abstract

These findings demonstrate that NA confers robust neuroprotection in DN by alleviating inflammation and oxidative stress, preserving neuronal structure and function, and reprogramming key metabolic pathways.

Frontiers in PharmacologyVol. 17
Hunter Genetics (AU), The Hunterian (GB), HealthInsight (US), State Institute for Drug Control (CZ), Zhejiang University (CN)
Openalex Percentile: Top 60%
Neurological Disorders and Treatments
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