Fine-Tuning a Small Vision Language Model Using Synthetic Data for Explaining Bacterial Skin Disease Images

<b>Background/Objectives:</b> Vision language models (VLMs) show strong potential for medical image understanding, but their large scale often limits practical deployment. This study investigates whether a compact VLM can be effectively adapted for dermatology, with a focus on explaining bacterial skin disease images. <b>Methods:</b> We curate a dataset derived from PMC-OA using the BIOMEDICA dataset and construct PMC-derma-VQA-bacteria by pairing images with inherited figure captions and synthetically generated question-answer (QA) supervision produced by Google's Gemini model. SmolVLM is fine-tuned under three supervision settings: QA-only, caption-only, and a combined QA+caption strategy. The models are evaluated on a held-out test set for both text-generation quality and diagnostic classification performance. <b>Results:</b> QA-only supervision yields the best report-generation performance, while the combined QA+caption setting achieves the highest classification accuracy (70.20%). <b>Conclusions:</b> Synthetic QA supervision can meaningfully enhance compact VLMs for medical image understanding and diagnostic support in dermatology.

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Publication Details

Journal
Diagnostics
Published
2026-02-18
DOI
https://doi.org/10.3390/diagnostics16040603
Primary Topic
Multimodal Machine Learning Applications
Type
article
Field-Weighted Citation Impact
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article

Fine-Tuning a Small Vision Language Model Using Synthetic Data for Explaining Bacterial Skin Disease Images

Gülsüm Gençoğlan, S. Zhang, Burak Temelkuran, Abdurrahim Yilmaz
Diagnostics
Multimodal Machine Learning Applications
article

Fine-Tuning a Small Vision Language Model Using Synthetic Data for Explaining Bacterial Skin Disease Images

Gülsüm Gençoğlan, S. Zhang, Burak Temelkuran, Abdurrahim Yilmaz
article en

Abstract

<b>Background/Objectives:</b> Vision language models (VLMs) show strong potential for medical image understanding, but their large scale often limits practical deployment. This study investigates whether a compact VLM can be effectively adapted for dermatology, with a focus on explaining bacterial skin disease images. <b>Methods:</b> We curate a dataset derived from PMC-OA using the BIOMEDICA dataset and construct PMC-derma-VQA-bacteria by pairing images with inherited figure captions and synthetically generated question-answer (QA) supervision produced by Google's Gemini model. SmolVLM is fine-tuned under three supervision settings: QA-only, caption-only, and a combined QA+caption strategy. The models are evaluated on a held-out test set for both text-generation quality and diagnostic classification performance. <b>Results:</b> QA-only supervision yields the best report-generation performance, while the combined QA+caption setting achieves the highest classification accuracy (70.20%). <b>Conclusions:</b> Synthetic QA supervision can meaningfully enhance compact VLMs for medical image understanding and diagnostic support in dermatology.

DiagnosticsVol. 16(4)
Turkish Society of Cardiology (TR), Imperial College London (GB)
Quality Education
Openalex Percentile: Top 52%
Multimodal Machine Learning Applications
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