Case Report: Syncope in an 11-year-old girl induced by anomalous aortic origin of the coronary artery, initially diagnosed via echocardiography

Anomalous aortic origin of the coronary artery (AAOCA) is a relatively rare congenital coronary anomaly identified as a common cause of exercise-induced cardiac syncope and sudden death in young individuals. In most cases, the coronary artery courses between the aorta and pulmonary artery, exhibiting an intramural trajectory within the aortic wall. Herein, we present a case of an 11-year-old girl with AAOCA manifesting with sudden-onset syncope complicated by myocardial infarction as the initial symptom, along with a discussion of the underlying pathogenesis. This case is important as it highlights the fact that comprehensive coronary artery evaluation combined with high-quality imaging modalities is critical to enhance the diagnostic accuracy of coronary anomalies. As such, TTE should be established as an important first-line tool within a multimodality imaging pathway. for AAOCA.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2026-02-18
DOI
https://doi.org/10.3389/fcvm.2026.1632958
Primary Topic
Coronary Artery Anomalies
Type
article
Field-Weighted Citation Impact
0.00

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article

Case Report: Syncope in an 11-year-old girl induced by anomalous aortic origin of the coronary artery, initially diagnosed via echocardiography

Q. Liu, Jianjun Wang, Dong Wang, Yuting Wu et al.
Frontiers in Cardiovascular Medicine
Coronary Artery Anomalies
article

Case Report: Syncope in an 11-year-old girl induced by anomalous aortic origin of the coronary artery, initially diagnosed via echocardiography

Q. Liu, Jianjun Wang, Dong Wang, Yuting Wu, Xiaomei Li, Xiangqun Sun, Wenlong Wang
article en

Abstract

Anomalous aortic origin of the coronary artery (AAOCA) is a relatively rare congenital coronary anomaly identified as a common cause of exercise-induced cardiac syncope and sudden death in young individuals. In most cases, the coronary artery courses between the aorta and pulmonary artery, exhibiting an intramural trajectory within the aortic wall. Herein, we present a case of an 11-year-old girl with AAOCA manifesting with sudden-onset syncope complicated by myocardial infarction as the initial symptom, along with a discussion of the underlying pathogenesis. This case is important as it highlights the fact that comprehensive coronary artery evaluation combined with high-quality imaging modalities is critical to enhance the diagnostic accuracy of coronary anomalies. As such, TTE should be established as an important first-line tool within a multimodality imaging pathway. for AAOCA.

Frontiers in Cardiovascular MedicineVol. 13
Binzhou Medical University (CN), Shandong University of Aeronautics (CN), Binzhou Medical College Hospital (CN)
National Natural Science Foundation of China, China Postdoctoral Science Foundation, Binzhou Medical University, Medical and Health Science and Technology Development Project of Shandong Province
Good health and well-being
Openalex Percentile: Top 50%
Coronary Artery Anomalies
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Case Report: Syncope in an 11-year-old girl induced by anomalous aortic origin of the coronary artery, initially diagnosed via echocardiography — Q. Liu, Jianjun Wang, et al. · Frontiers in Cardiovascular Medicine (2026) | TGRS Research Map | TGRS