Tobacco craving and suicidal risk in a cohort of subjects with schizophrenia: results from the national FACE-SZ cohort
These findings highlight the complex interplay between clinical severity, substance use, and suicidality in shaping craving levels among patients with schizophrenia. Mediation analyses showed that AUD does not explain the craving-suicide relationship, indicating that these represent separate, parallel risk pathways. Assessment of tobacco craving and comorbid substance use, particularly AUD, is essential when assessing suicide risk. These findings have important implications for suicide prevention and treatment strategies in individuals with schizophrenia and co-occurring substance use disorders.
Authors
- Fabrice Berna
- Baptiste Pignon
- Yecodji Dansou
- Melina Fatseas
- J.M. Dorey
- Ophélia Godin
- Arnaud Tessier
- O Blanc
- Caroline Dubertret
- J Dubos
- S Leignier
- I Chereau-Boudet
- E Very
- Andrei Szöke
- M Urbach
- C Andrieu-Haller
- J Mallet
- Nathalie Coulon
- P Peri
- C Dubertret
- E Salvat
- T. Michel
- Christine Passerieux
- Pierre-Michel Llorca
- Fabrice Berna
- R Dassing
- E Metairie
- Mathieu Urbach
- Romain Rey
- PM Llorca
- N Coulon
- C Passerieux
- M Jarroir
- M Cléry
- D Misdrahi
- A Szöke
- B Schorr
- Laurent Boyer
- M Andre
- A Tessier
- Jasmina Mallet
- Thierry D'amato
- A Ascarain
- F Gabayet
- B Pignon
- R Rey
- D Capdevielle
- David Misdrahi
- E Bourguignon
- G Fond
- Cristobal Belmonte
- J Clauss-Kobayashi
- C Portalier
- Guillaume Fond
- M Leboyer
- F Schürhoff
- C Roman
- A Esselin
- E Fakra
- D Lacelle
- A Zinetti-Bertschy
- Sylvain Leigner
- Isabelle Chereau
- Franck Schürhoff
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Délégation Paris 5 (FR)
- Université d'Orléans (FR)
- Centre National de la Recherche Scientifique (FR)
- Université de Bordeaux (FR)
- Inserm (FR)
- Délégation Paris 7 (FR)
- Université Paris-Est Créteil (FR)
- Université Paris Cité (FR)
- Aix-Marseille Université (FR)
- Université Paris-Saclay (FR)
- Centre Hospitalier Universitaire de Bordeaux (FR)
- Centre de Recherche en Neurosciences de Lyon (FR)
- Fondation FondaMental (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Centre de recherche en Epidémiologie et Santé des Populations (FR)
- Bordeaux Population Health (FR)
- Laboratoire d’Informatique Fondamentale de Marseille (FR)
- Centre Hospitalier Le Vinatier (FR)
- Centre Hospitalier Charles Perrens (FR)
- Institut Mondor de Recherche Biomédicale (FR)
- Université de Strasbourg (FR)
Publication Details
- Journal
- Psychiatry Research
- Published
- 2026-02-19
- DOI
- https://doi.org/10.1016/j.psychres.2026.117028
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00