Guideline Adherence of Perioperative Antibiotics and Surgical Site Infections in Noncardiac Surgery
This cross-sectional study found that IDSA guideline nonadherence, including incorrect antibiotic choice and missed intraoperative redosing, was common and associated with increased SSI risk, despite high adherence to SCIP timing metrics. Improving adherence to IDSA-recommended antibiotic selection and redosing may meaningfully reduce SSIs.
Authors
- George F. Michel (ORCID: https://orcid.org/0000-0003-3415-8925)
- Michael R. Mathis (ORCID: https://orcid.org/0000-0002-9697-2212)
- Mabel Wai
- Clark Fisher (ORCID: https://orcid.org/0000-0003-0707-1613)
- Douglas Colquhoun
- Jill M. Mhyre (ORCID: https://orcid.org/0000-0002-6444-3025)
- Robert B. Schonberger (ORCID: https://orcid.org/0000-0002-5180-5189)
- Kevin M. Shuster
- Sachin Kheterpal
- Amit Bardia (ORCID: https://orcid.org/0000-0002-0841-9442)
- Xiwen Zhao (ORCID: https://orcid.org/0009-0004-8464-2402)
- Michael McGee
- Hung-Mo Lin
Institutions
- Yale New Haven Hospital (US)
- Harvard University (US)
- University of Michigan (US)
- Yale University (US)
- Massachusetts General Hospital (US)
- University of Arkansas for Medical Sciences (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2026-02-18
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.59349
- Primary Topic
- Surgical site infection prevention
- Type
- article
- Field-Weighted Citation Impact
- 0.00