Optimal Compatibility of Main Effective Parts of Astragali Radix‐Safflower for the Treatment of Cerebral Ischemia/Reperfusion by Pharmacokinetics‐Pharmacodynamics Analysis Based on Microdialysis and Liquid Chromatography–Tandem Mass Spectrometry
The different compatibility of effective parts of traditional Chinese medicine would influence the pharmacokinetics parameters of each active component in CI/RI rats. Orthogonal compatibility and total statistical moment method provided a way to find the best compatibility. This study provided a pattern for the exploration of traditional Chinese medicine compatibility.
Authors
- Chang Li (ORCID: https://orcid.org/0000-0002-3267-1859)
- Yu Du (ORCID: https://orcid.org/0000-0002-4585-8989)
- Peng Zhou (ORCID: https://orcid.org/0009-0000-5536-1506)
- Yu He
- Xinyu Dong
- Qiaomei Lou
Institutions
- Zhejiang Chinese Medical University (CN)
Publication Details
- Journal
- Phytochemical Analysis
- Published
- 2026-02-18
- DOI
- https://doi.org/10.1002/pca.70055
- Primary Topic
- Traditional Chinese Medicine Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00