Real‐World Use of Cenobamate in Paediatric Drug‐Resistant Epilepsy: Long‐Term Efficacy, Safety, and Co‐Medication Adjustment
Our study confirms and extends recent evidence on the efficacy and favourable tolerability of cenobamate in paediatric drug-resistant epilepsy. We observed functional improvements and polytherapy simplification, suggesting broader therapeutic benefits. These findings warrant prospective validation in specific paediatric epilepsy syndromes and may help support regulatory approval for paediatric use.
Authors
- Simona Pellacani (ORCID: https://orcid.org/0000-0003-3578-8953)
- Luca Bartolini (ORCID: https://orcid.org/0000-0003-2755-8218)
- Martina Lombardini
- Mara Cavallin (ORCID: https://orcid.org/0000-0002-0133-7620)
- Erica Scuma
- Carmen Barba
- R. Guerrini
- Saverio Caini
- Alessandra Boncristiano
- Simona Balestrini
- Tiziana Pisano
Institutions
- Prevention Institute (US)
- Meyer Children's Hospital (IT)
- University of Florence (IT)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1111/ene.70530
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00