Intravitreal Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema in Türkiye: 48-Month Data, BOSPHORUS-DME Study Group Report No. 1

This is the largest and longest real-world study on DME treatment conducted in Türkiye. It demonstrates that visual and anatomical gains can be sustained over a 48-month period. While the overall trend aligns with previous real-world studies, the higher injection frequency in our cohort appears to have contributed to more favorable outcomes. These findings underscore the importance of early intensive therapy and sustained treatment adherence in the real-world management of DME.

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Publication Details

Journal
Turkish Journal of Ophthalmology
Published
2026-02-18
DOI
https://doi.org/10.4274/tjo.galenos.2026.67863
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Intravitreal Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema in Türkiye: 48-Month Data, BOSPHORUS-DME Study Group Report No. 1

Abdullah Özkaya, Dilan Yıldız, Mustafa Hepokur, Turgay Uçak et al.
Turkish Journal of Ophthalmology
Retinal Diseases and Treatments
article

Intravitreal Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema in Türkiye: 48-Month Data, BOSPHORUS-DME Study Group Report No. 1

Abdullah Özkaya, Dilan Yıldız, Mustafa Hepokur, Turgay Uçak, Anıl Korkmaz, Akın ÇAKIR, Ece Özal, Sadık Altan Özal, Şerife Çiloğlu Hayat, Serhat Ermiş, İbrahim Koçak, Veysel Levent Karabaş, Nihat Sayın, Mehmet Egemen Karataş, Ecem Önder Tokuç, Bengi Demirayak, Mine Öztürk, Mehmet Erdoğan, Murat Arıcı, Semra Tiryaki Demir, İsmail Umut Onur, Gamze Karataş, Murat Karapapak
article en

Abstract

This is the largest and longest real-world study on DME treatment conducted in Türkiye. It demonstrates that visual and anatomical gains can be sustained over a 48-month period. While the overall trend aligns with previous real-world studies, the higher injection frequency in our cohort appears to have contributed to more favorable outcomes. These findings underscore the importance of early intensive therapy and sustained treatment adherence in the real-world management of DME.

Turkish Journal of OphthalmologyVol. 56(1)
Tekirdağ Namık Kemal University (TR), University of Health Science (KH), Haseki Eğitim ve Araştırma Hastanesi (TR), Memorial Sisli Hospital (TR), Istanbul University-Cerrahpaşa (TR), Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi (TR), Sağlık Bilimleri Üniversitesi (TR), İstanbul Başakşehir Çam ve Sakura Şehir Hastanesi, Kocaeli Üniversitesi (TR), University of Health Sciences Antigua (AG)
Kocaeli Üniversitesi
Good health and well-being
Openalex Percentile: Top 51%
Retinal Diseases and Treatments
DOIOpen Access PDFOpenAlex
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