Pyroptosis-mediator Gasdermin D in serum: a potential biomarker in diabetic kidney disease
Serum GSDMD levels are significantly associated with diabetic kidney disease and renal dysfunction. These findings suggest that GSDMD may serve as a complementary biomarker for DKD assessment; however, longitudinal and multicenter studies are required to confirm its prognostic value and clinical applicability.
Authors
- Fang Yu
- Xuexin Liu (ORCID: https://orcid.org/0000-0001-9799-0730)
- Nan Ding (ORCID: https://orcid.org/0000-0003-3116-7498)
- Lijing Huo (ORCID: https://orcid.org/0009-0000-7417-6699)
- Chen Yang (ORCID: https://orcid.org/0000-0002-6005-0400)
- Changmei Wei
- Qiong Liu
Institutions
- Hebei General Hospital (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2026-02-18
- DOI
- https://doi.org/10.3389/fendo.2026.1734036
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00