A Combination of Amaranth Protein Hydrolysate and Korean Mint Extract Ameliorates Cisplatin-Induced Nephrotoxicity and Cachexia in CT26 Tumor-Bearing BALB/c Mice
These findings demonstrate that AKE confers comprehensive protection against cisplatin-induced cachexia and nephrotoxicity by coordinately preserving muscle and adipose tissue and attenuating renal injury, suggesting its potential as a functional nutritional strategy to alleviate chemotherapy-associated tissue wasting.
Authors
- Yeeun Kim (ORCID: https://orcid.org/0000-0003-2764-5709)
- Dong-Woo Lee
- Jae-Kwan Hwang
- Mi-Bo Kim
- Ju Hyun Park
- Daedong Kim
- Junhee Lee
Institutions
- Yonsei University (KR)
- Daewoong Pharmaceutical (South Korea) (KR)
- Pukyong National University (KR)
Publication Details
- Journal
- Nutrients
- Published
- 2026-02-18
- DOI
- https://doi.org/10.3390/nu18040665
- Primary Topic
- Chemotherapy-induced organ toxicity mitigation
- Type
- article
- Field-Weighted Citation Impact
- 0.00