Associations between hair endocannabinoid concentrations and parental depressive symptoms: A longitudinal study of mothers, fathers, and their offspring up to two years postpartum
Findings suggest that rather than altered hair endocannabinoids and N-acylethanolamines predicting PPDS, depressive psychopathology may be associated with AEA signalling over time in a community cohort of mothers and fathers. Potential intergenerational effects of PPDS via the ECS require further exploration. Future research in high-risk samples and with a broader covariate adjustment is needed to inform possible interventive approaches.
Authors
- Lydia Rihm (ORCID: https://orcid.org/0000-0001-9733-2391)
- Luisa Bergunde (ORCID: https://orcid.org/0000-0001-6790-8679)
- Tilmann von Soest (ORCID: https://orcid.org/0000-0002-5576-2059)
- Kerstin Weidner (ORCID: https://orcid.org/0009-0007-9140-4068)
- Isabel Jaramillo (ORCID: https://orcid.org/0000-0003-2661-4505)
- Susann Steudte‐Schmiedgen
- S. Garthus-Niegel
- W. Gao
Institutions
- Nanjing Normal University (CN)
- University of Oslo (NO)
- University Hospital Carl Gustav Carus (DE)
Publication Details
- Journal
- Progress in Neuro-Psychopharmacology and Biological Psychiatry
- Published
- 2026-02-18
- DOI
- https://doi.org/10.1016/j.pnpbp.2026.111649
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00