Intravenous Pamidronate in Persistent Complex Regional Pain Syndrome (CRPS): A Retrospective Observational Study on Effectiveness and Tolerability

In patients with predominantly persistent CRPS, intravenous pamidronate was well tolerated and associated with a modest, short-term pain relief up to 3 months. No sustained analgesic benefit was evident at later timepoints.

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Publication Details

Journal
Journal of Pain Research
Published
2026-02-01
DOI
https://doi.org/10.2147/jpr.s573167
Primary Topic
Pain Management and Treatment
Type
article
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article

Intravenous Pamidronate in Persistent Complex Regional Pain Syndrome (CRPS): A Retrospective Observational Study on Effectiveness and Tolerability

Maaike Dirckx, Sanne E. Hoeks, Paul van Daele, Frank J. P. M. Huygen et al.
Journal of Pain Research
Pain Management and Treatment
article

Intravenous Pamidronate in Persistent Complex Regional Pain Syndrome (CRPS): A Retrospective Observational Study on Effectiveness and Tolerability

Maaike Dirckx, Sanne E. Hoeks, Paul van Daele, Frank J. P. M. Huygen, Daniël van der Spek
article en

Abstract

In patients with predominantly persistent CRPS, intravenous pamidronate was well tolerated and associated with a modest, short-term pain relief up to 3 months. No sustained analgesic benefit was evident at later timepoints.

Journal of Pain ResearchVol. Volume 19
Erasmus MC (NL)
Good health and well-being
Openalex Percentile: Top 51%
Pain Management and Treatment
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Intravenous Pamidronate in Persistent Complex Regional Pain Syndrome (CRPS): A Retrospective Observational Study on Effectiveness and Tolerability — Maaike Dirckx, Sanne E. Hoeks, et al. · Journal of Pain Research (2026) | TGRS Research Map | TGRS