The use of non-TNF targeted biologics in Behçet’s Disease: Real-life data from the International AIDA Network Behçet’s Disease Registry
Biologics targeting IL-1, IL-6, IL-17, and IL-12/23 pathways may offer therapeutic alternatives in BD patients unresponsive to TNF-α inhibitors. The treatment efficacy varies across phenotypes, highlighting the need for individualized treatment decisions.
Authors
- Stefano Gentileschi (ORCID: https://orcid.org/0000-0001-9682-4706)
- Gaafar Ragab (ORCID: https://orcid.org/0000-0001-6529-0334)
- G. Lopalco
- F. Iannone
- Fatma Alıbaz-Öner (ORCID: https://orcid.org/0000-0002-6653-1758)
- C. Fabiani
- Valeria Caggiano (ORCID: https://orcid.org/0000-0002-9907-4856)
- Antonio Vitale (ORCID: https://orcid.org/0000-0003-4469-7332)
- Ombretta Viapiana (ORCID: https://orcid.org/0000-0003-1917-5655)
- Piero Ruscitti (ORCID: https://orcid.org/0000-0003-3487-8551)
- J. Sota
- Francesco Carubbi (ORCID: https://orcid.org/0000-0003-1958-5136)
- M. Frassi
- Alessandro Conforti
- Gizem Sevik
- Giacomo Emmi
- Matteo Piga (ORCID: https://orcid.org/0000-0002-1126-8315)
- Ibrahim Almaghlouth
- Abdurrahman Tufan
- Francesco Ciccia
- Andrés González-García
- Roberto Giacomelli
- Haner Direskeneli
- Antonella Insalaco
- Rosaria Talarico
- Luca Cantarini
Institutions
- University of Siena (IT)
- University of Pisa (IT)
- University of Trieste (IT)
- Cairo University (EG)
- Università Campus Bio-Medico (IT)
- University of Cagliari (IT)
- University of L'Aquila (IT)
- Monash Medical Centre (AU)
- King Saud University (SA)
- Rite Aid (United States) (US)
- Azienda Ospedaliera Universitaria Integrata Verona (IT)
- Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari (IT)
- Ospedale di Cattinara (IT)
- San Salvatore Hospital (IT)
- Autoimmune Technologies (United States) (US)
- Bambino Gesù Children's Hospital (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- Azienda Ospedaliera Universitaria Senese (IT)
- ERN GUARD-Heart (NL)
- Campus Bio Medico University Hospital (IT)
- Fondazione Cassa di Risparmio Civitavecchia (IT)
- The Memory Clinic (US)
- Center for Rheumatology (US)
- Hospital Universitario Ramón y Cajal (ES)
- October 6 University (EG)
- Azienda Ospedaliera Universitaria Pisana (IT)
- University of Bari Aldo Moro (IT)
- Marmara University (TR)
- University of Brescia (IT)
- Gazi University (TR)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2026-02-11
- DOI
- https://doi.org/10.1093/rheumatology/keag086
- Primary Topic
- Ocular Diseases and Behçet’s Syndrome
- Type
- article
- Field-Weighted Citation Impact
- 0.00