Exploratory Clinical Study to Evaluate the Efficacy and Safety of Sulfasalazine for Immune Checkpoint Inhibitor ( <scp>ICI</scp> )‐Induced Colitis
This exploratory study suggests that SSZ may be a useful option for mild-to-moderate ICI-induced colitis, but caution is warranted against SSZ-related hypersensitivity.
Authors
- Shintaro Akiyama (ORCID: https://orcid.org/0000-0003-0727-7638)
- Yoshinori Hiroshima
- Mariko Kobayashi
- Bryan J. Mathis (ORCID: https://orcid.org/0000-0002-9879-8289)
- Takashi Mamiya
- Akinori Sugaya
- Junji Hattori
- Shunsuke Ueyama
- Takeshi Yamada (ORCID: https://orcid.org/0000-0001-7848-5827)
- Yoshiyuki Yamamoto
Institutions
- University of Tsukuba (JP)
- Tsuchiura Kyodo General Hospital (JP)
- University of Tsukuba Hospital (JP)
- Ibaraki Prefectural Central Hospital (JP)
- Hitachi General Hospital (JP)
- Institute of Applied Biochemistry (JP)
- Saiseikai Ibaraki Hospital (JP)
Publication Details
- Journal
- JGH Open
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/jgh3.70365
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Tsukuba