The nationwide genomic characteristics and phylogenetic evolution of ST23-K1 hypervirulent Klebsiella pneumoniae in relation to virulence and antimicrobial resistance acquisition
ST23-K1 remains a hypervirulent lineage undergoing ongoing evolutionary expansion. The presence of acquired ARGs in ST23-K1 may be associated with AcrIE-harbouring IncFII plasmids, and functional validation is required to clarify the underlying mechanisms. Continuous genomic surveillance is essential to monitor the evolution and antimicrobial resistance trends of ST23-K1.
Authors
- Huangdu Hu (ORCID: https://orcid.org/0009-0002-0317-5722)
- Junxin Zhou
- Dongdong Zhao (ORCID: https://orcid.org/0000-0001-9691-1308)
- Rui Weng (ORCID: https://orcid.org/0000-0002-2519-2745)
- Weiyi Huang (ORCID: https://orcid.org/0009-0002-8155-5093)
- Xiaoxing Du
- Yinping Wang
- Jingjing Quan
- Qiucheng Shi
- Yunsong Yu
- Xinwei Chen
- Dongping Hu
- Yan Jiang
- Ping Zhang
Institutions
- Sir Run Run Shaw Hospital (CN)
- Hangzhou Medical College (CN)
Publication Details
- Journal
- Journal of Infection
- Published
- 2026-02-18
- DOI
- https://doi.org/10.1016/j.jinf.2026.106709
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00