Impact of an Additional Pregnancy on the Natural History of Insulin Sensitivity, β-Cell Function, and Glycemia in Parous Women

Pregnancy is associated with worsening of the long-term trajectory of insulin sensitivity, revealing both a pathophysiologic basis for enhanced diabetes risk and a target for risk modification.

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Publication Details

Journal
Diabetes Care
Published
2026-02-18
DOI
https://doi.org/10.2337/dc25-2354
Primary Topic
Gestational Diabetes Research and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Impact of an Additional Pregnancy on the Natural History of Insulin Sensitivity, β-Cell Function, and Glycemia in Parous Women

Bernard Zinman, Junwei Shen, Ravi Retnakaran, Anthony J. Hanley
Diabetes Care
Gestational Diabetes Research and Management
article

Impact of an Additional Pregnancy on the Natural History of Insulin Sensitivity, β-Cell Function, and Glycemia in Parous Women

Bernard Zinman, Junwei Shen, Ravi Retnakaran, Anthony J. Hanley
article en

Abstract

Pregnancy is associated with worsening of the long-term trajectory of insulin sensitivity, revealing both a pathophysiologic basis for enhanced diabetes risk and a target for risk modification.

Diabetes CareVol. 49(4)
Mount Sinai Hospital (CA), University of Toronto (CA), Lunenfeld-Tanenbaum Research Institute (CA)
Good health and well-being
Openalex Percentile: Top 48%
Gestational Diabetes Research and Management
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