Reducing Early-Life Smoke Exposure as a Preventive Strategy for Pediatric Multiple Sclerosis: Results from the PEDIGREE Study
Parental smoking, particularly paternal smoking current habit and before pregnancy, may increase the risk of PedMS. Promoting smoke-free behaviors among parents could therefore represent a feasible preventive approach to limit early-life environmental factors involved in disease susceptibility.
Authors
- Maurizio Viri (ORCID: https://orcid.org/0000-0003-2701-8254)
- Alen Zollo (ORCID: https://orcid.org/0009-0005-0908-7469)
- Agnese Suppiej (ORCID: https://orcid.org/0000-0001-5130-1450)
- Marzia Fronza
- Angela Lucia Berardinelli (ORCID: https://orcid.org/0000-0002-4645-8055)
- Silvy Pilotto (ORCID: https://orcid.org/0000-0001-7950-0136)
- Borriello Giovanna
- Antonio Gallo (ORCID: https://orcid.org/0000-0002-4045-3237)
- Marta Simone (ORCID: https://orcid.org/0000-0001-7924-1461)
- Sandra D'Alfonso
- Simona Malucchi
- Giacomo Lus
- Lucia Moiola
- Martina Tosi
- Alessandra Protti
- Nicola Pomella
- Maria Trojano
- Sarah Rasia
- Carlotta Canavese
- Pietro Annovazzi
- Andrea Corona
- Roberta Lanzillo
- the PEDIGREE Study Group
- Filippo Martinelli-Boneschi
- Valentina Tomassini
- Stefania Maria Bova
- Luigi Grimaldi
- Eleonora Cocco
- Roberto Bergamaschi
- Maria Pia Amato
- Marta Zaffira Conti
- Giovanna De Luca
- Angelo Ghezzi
- Valentina Torri Clerici
- Alberto Priori
Institutions
- Università degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT)
- AOL (United States) (US)
- University of Sassari (IT)
- University of Cagliari (IT)
- University of Milan (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- University of Ferrara (IT)
- Foundation Center (US)
- University of Chieti-Pescara (IT)
- Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT)
- Saint Camillus International University of Health and Medical Sciences (IT)
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT)
- Urology Foundation (GB)
- Ospedale Papa Giovanni XXIII (IT)
- Fatebenefratelli Hospital (IT)
- Don Carlo Gnocchi Foundation (IT)
- Azienda Socio Sanitaria Territoriale Lariana (IT)
- Fondazione Istituto G. Giglio di Cefalù (IT)
- Ospedale Regina Margherita (IT)
- Ospedale dei Bambini Vittore Buzzi (IT)
- Azienda Ospedaliera Sant’Antonio Abate di Gallarate (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Ospedale San Luigi Gonzaga (IT)
- Fondazione IRCCS Istituto Neurologico Carlo Besta (IT)
- Ospedale San Pietro Fatebenefratelli (IT)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
- Azienda Socio Sanitaria Territoriale della Valle Olona
- University of Florence (IT)
- University of Bari Aldo Moro (IT)
- University of Naples Federico II (IT)
- Union des Industries Ferroviaires Européennes (BE)
Publication Details
- Journal
- Neurology and Therapy
- Published
- 2026-02-18
- DOI
- https://doi.org/10.1007/s40120-026-00896-1
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fondazione Italiana Sclerosi Multipla