Prolonged corrected QT interval and Torsades de pointes following electrical cardioversion of atrial fibrillation in a young woman

Electrical cardioversion is a widely used and generally safe procedure for restoring sinus rhythm in atrial fibrillation. However, it may rarely precipitate significant proarrhythmic complications. We report the case of a 35-year-old woman with a history of atrial septal defect closure who presented with persistent symptomatic atrial fibrillation. She underwent successful synchronized direct current cardioversion, but immediately developed marked prolongation of the corrected QT interval (>600 ms) followed by recurrent episodes of torsades de pointes, one requiring defibrillation. Intravenous magnesium was administered, but QT prolongation persisted in association with hypotension and bradycardia. Dopamine infusion was initiated to increase heart rate, which contributed to gradual QT normalization. The patient recovered fully without recurrence of arrhythmia. This case highlights a rare but potentially life-threatening complication of cardioversion and underscores the importance of vigilant post-procedural monitoring and timely intervention, even in patients without prior repolarization abnormalities.

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Publication Details

Journal
Oxford Medical Case Reports
Published
2025-12-11
DOI
https://doi.org/10.1093/omcr/omaf295
Primary Topic
Cardiac electrophysiology and arrhythmias
Type
article
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article

Prolonged corrected QT interval and Torsades de pointes following electrical cardioversion of atrial fibrillation in a young woman

Anas Bedawi Babiker, Hassan Elzain, Jasem H Redha, Karar Mahmoud Nadir Mohamed et al.
Oxford Medical Case Reports
Cardiac electrophysiology and arrhythmias
article

Prolonged corrected QT interval and Torsades de pointes following electrical cardioversion of atrial fibrillation in a young woman

Anas Bedawi Babiker, Hassan Elzain, Jasem H Redha, Karar Mahmoud Nadir Mohamed, Mohamed Elkalifa Elawad Elhassan, Heba Fathy Ismail, Mohamed Adel Mostafa
article en

Abstract

Electrical cardioversion is a widely used and generally safe procedure for restoring sinus rhythm in atrial fibrillation. However, it may rarely precipitate significant proarrhythmic complications. We report the case of a 35-year-old woman with a history of atrial septal defect closure who presented with persistent symptomatic atrial fibrillation. She underwent successful synchronized direct current cardioversion, but immediately developed marked prolongation of the corrected QT interval (>600 ms) followed by recurrent episodes of torsades de pointes, one requiring defibrillation. Intravenous magnesium was administered, but QT prolongation persisted in association with hypotension and bradycardia. Dopamine infusion was initiated to increase heart rate, which contributed to gradual QT normalization. The patient recovered fully without recurrence of arrhythmia. This case highlights a rare but potentially life-threatening complication of cardioversion and underscores the importance of vigilant post-procedural monitoring and timely intervention, even in patients without prior repolarization abnormalities.

Oxford Medical Case ReportsVol. 2026(2)
University of Khartoum (SD), University Hospitals of North Midlands NHS Trust (GB), Letterkenny University Hospital (IE), Kuwait Institute for Medical Specialization (KW), Care International (CH), Ministry of Health (KW), Sudan Medical Specialization Board (SD)
Openalex Percentile: Top 25%
Cardiac electrophysiology and arrhythmias
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