Permissive Cardiotoxicity in HER2-Positive Metastatic Breast Cancer With Moderate Left Ventricular Dysfunction
Optimal GDMT supports cardiac recovery in patients with asymptomatic left ventricular dysfunction, allowing for continued HER2 therapy. Integrated cardio-oncology care is essential to balance cancer control with cardiovascular safety.
Authors
- Pramukh Arun Kumar (ORCID: https://orcid.org/0000-0003-3497-1334)
- Agnes Kim
- Humza Shamoon Rashid
Institutions
- University of Connecticut (US)
- UConn Health (US)
Publication Details
- Journal
- JACC Case Reports
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.jaccas.2025.106555
- Citations
- 1
- Primary Topic
- Chemotherapy-induced cardiotoxicity and mitigation
- Type
- article
- Field-Weighted Citation Impact
- 30.07