Integrated Methylome–Transcriptome Analysis Reveals Epigenomic Remodeling and Rho <scp>GTPase</scp> –Linked Immune–Epithelial Crosstalk in Atopic Dermatitis

Our study underscores the importance of epigenomic remodeling in AD and highlights potential avenues for precision intervention in chronic inflammatory skin disease.

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Publication Details

Journal
Allergy
Published
2026-02-17
DOI
https://doi.org/10.1111/all.70259
Primary Topic
Dermatology and Skin Diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Integrated Methylome–Transcriptome Analysis Reveals Epigenomic Remodeling and Rho GTPase –Linked Immune–Epithelial Crosstalk in Atopic Dermatitis

Y. Yang, Harri Alenius, Tiina Skoog, Péter Oláh et al.
Allergy
Dermatology and Skin Diseases
article

Integrated Methylome–Transcriptome Analysis Reveals Epigenomic Remodeling and Rho GTPase –Linked Immune–Epithelial Crosstalk in Atopic Dermatitis

Y. Yang, Harri Alenius, Tiina Skoog, Péter Oláh, Piia Karisola, Shintaro Katayama, Juha Kere, Björn Andersson, Stephan Weidinger, Catherine Smith, Nanna Fyhrquist, Antti Lauerma, Jonathan Barker
article en

Abstract

Our study underscores the importance of epigenomic remodeling in AD and highlights potential avenues for precision intervention in chronic inflammatory skin disease.

Allergy
University of Helsinki (FI), King's College London (GB), Karolinska Institutet (SE), Humak University of Applied Sciences (FI), Düsseldorf University Hospital (DE), University Hospital Schleswig-Holstein (DE), Folkhälsans Forskningscentrum (FI), Karlstad University (SE), Heinrich Heine University Düsseldorf (DE), University of Pecs (HU), University of Lübeck (DE)
Helsingin Yliopisto
Openalex Percentile: Top 50%
Dermatology and Skin Diseases
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