Effects of arginine‐enriched enteral nutrition on clinical outcomes with infectious events and muscle volume in critically ill patients: A systematic review and meta‐analysis

Arginine-enriched EN may not exert beneficial effects on the incidence of infection or other outcomes. However, because no studies have examined the administration of arginine alone and few RCTs investigated physical outcomes, such as muscle volume and physical function, further research is warranted.

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Publication Details

Journal
Journal of Parenteral and Enteral Nutrition
Published
2026-02-17
DOI
https://doi.org/10.1002/jpen.70068
Primary Topic
Clinical Nutrition and Gastroenterology
Type
article
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article

Effects of arginine‐enriched enteral nutrition on clinical outcomes with infectious events and muscle volume in critically ill patients: A systematic review and meta‐analysis

Naoki Higashibeppu, Masayuki Kaku, Chihiro Narita, H Murata et al.
Journal of Parenteral and Enteral Nutrition
Clinical Nutrition and Gastroenterology
article

Effects of arginine‐enriched enteral nutrition on clinical outcomes with infectious events and muscle volume in critically ill patients: A systematic review and meta‐analysis

Naoki Higashibeppu, Masayuki Kaku, Chihiro Narita, H Murata, Kensuke Nakamura, R. Yamamoto, Kohei Yamada, Hideaki Sakuramoto, Joji Kotani, Minoru Yoshida
article en

Abstract

Arginine-enriched EN may not exert beneficial effects on the incidence of infection or other outcomes. However, because no studies have examined the administration of arginine alone and few RCTs investigated physical outcomes, such as muscle volume and physical function, further research is warranted.

Journal of Parenteral and Enteral Nutrition
Kyorin University (JP), Keio University (JP), Kyoto Medical Center (JP), National Defense Medical College Hospital (JP), Keio University Hospital (JP), Shizuoka City Hospital (JP), Shizuoka General Hospital (JP), Japan Clinical Cancer Research Organization (JP), Kumamoto Medical Center (JP), Kobe University (JP), Kindai University (JP)
Zero hunger
Openalex Percentile: Top 49%
Clinical Nutrition and Gastroenterology
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