High-definition tDCS regulate the prefrontal-limbic-striatal connectivity and reduce depression in youth with first-episode depression
This study suggests that tDCS may be an effective intervention for young adults with FED. The improvement in depressive symptoms induced by tDCS was associated with modulation of brain connectivity in cortical and subcortical regions within the prefrontal-limbic-striatal system. Our study provides novel neurobiological evidence for the treatment of depression with tDCS.
Authors
- Huajia Tang
- Jiali Liu (ORCID: https://orcid.org/0000-0002-1586-5221)
- Xiaoping Wang
- Peiqu Liu
- Jiansong Zhou
- Hui Chen
- Fengmei Lu
Institutions
- Central South University (CN)
- Jishou University (CN)
- University of Electronic Science and Technology of China (CN)
- Shenzhen KangNing Hospital (CN)
- National Clinical Research (US)
- Jinzhou Kangning Hospital (CN)
Publication Details
- Journal
- BMC Psychiatry
- Published
- 2026-02-18
- DOI
- https://doi.org/10.1186/s12888-026-07881-w
- Primary Topic
- Attention Deficit Hyperactivity Disorder
- Type
- article
- Field-Weighted Citation Impact
- 0.00