DRP1 depletion protects NK cells from hypoxia-induced dysfunction
These findings indicate that DRP1 inactivation supports NK cell function in hypoxia and metabolic engineering may enhance CAR-NK efficacy in solid tumors.
Authors
- Diana Campillo-Davó (ORCID: https://orcid.org/0000-0002-6080-3935)
- Maxim Le Compte (ORCID: https://orcid.org/0000-0002-5587-4392)
- Astrid Van den Eynde
- Rafael J. Argüello (ORCID: https://orcid.org/0000-0001-9785-3883)
- Eva Lion (ORCID: https://orcid.org/0000-0002-2420-0301)
- Peter Verstraelen (ORCID: https://orcid.org/0000-0002-2214-2806)
- G. Roeyen
- An Wouters (ORCID: https://orcid.org/0000-0001-7771-1239)
- Felicia Rodrigues Fortes
- Laura Gehrcken (ORCID: https://orcid.org/0000-0003-0216-9208)
- Jorrit De Waele (ORCID: https://orcid.org/0000-0002-9999-6156)
- Winnok H. De Vos (ORCID: https://orcid.org/0000-0003-0960-6781)
- H. Prenen
- Tias Verhezen (ORCID: https://orcid.org/0000-0002-5264-599X)
- Jöran Melis (ORCID: https://orcid.org/0000-0003-0776-7936)
- Christophe Deben (ORCID: https://orcid.org/0000-0001-8085-2040)
- Sanne van der Heijden (ORCID: https://orcid.org/0000-0002-1271-652X)
- Evelien Smits
- Louize Brants
- Gabriele Palmiotto
- S. Van Laere
- Jonas Van Audenaerde
- Ho Wa Lau
- Filip Lardon
Institutions
- University of Antwerp (BE)
- Antwerp University Hospital (BE)
- Centre d’Immunologie de Marseille-Luminy (FR)
- University of Bologna (IT)
Publication Details
- Journal
- Redox Report
- Published
- 2026-02-18
- DOI
- https://doi.org/10.1080/13510002.2026.2626181
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.00