Impact of Thyroxine Treatment on Myelination in Premature Neonates With Intraventricular Hemorrhage: An Magnetic Resonance Imaging–Based Approach
The data suggest that T<sub>4</sub> treatment enhances white matter recovery and myelination in neonates with moderate-to-severe IVH. This pilot study establishes a solid foundation for confirming this effect through a large multicenter clinical trial in preterm neonates with IVH.
Authors
- Edmund F. LaGamma (ORCID: https://orcid.org/0000-0001-9720-1949)
- Praveen Ballabh (ORCID: https://orcid.org/0000-0002-2387-3942)
- Ashok Kumar Panigrahy
- Vincent Lee
Institutions
- Albert Einstein College of Medicine (US)
- University of Pittsburgh (US)
- Maria Fareri Children's Hospital (US)
Publication Details
- Journal
- Pediatric Neurology
- Published
- 2026-02-19
- DOI
- https://doi.org/10.1016/j.pediatrneurol.2026.02.005
- Primary Topic
- Neonatal and fetal brain pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute of Neurological Disorders and Stroke