Associations of metformin and sulfonylurea on vascular complications in early‐ and late‐onset type 2 diabetes: A cohort study
Sulfonylurea therapy was linked to increased cardiovascular risk, particularly in younger patients, while microvascular outcomes were comparable. These findings support metformin as the preferred first-line therapy for early-onset type 2 diabetes.
Authors
- Mingjuan Jin (ORCID: https://orcid.org/0000-0003-2358-0186)
- Jiayun Zhang (ORCID: https://orcid.org/0000-0003-4369-2126)
- L Shur Yu
- Yonghao Wu
- Lisha Xu
- Kun Chen (ORCID: https://orcid.org/0000-0003-3146-2577)
- Zongming Yang (ORCID: https://orcid.org/0000-0002-5480-9273)
- Jianbing Wang (ORCID: https://orcid.org/0000-0002-5571-2174)
- Yexiang Sun (ORCID: https://orcid.org/0009-0005-7258-138X)
- L M Shui
- Zhiqin Jiang
- P Shen
- H Lin
- Mengling Tang
- Ye Jiao
Institutions
- Anhui Medical University (CN)
- Ningbo Science and Technology Bureau (CN)
- Ningbo Center for Disease Control and Prevention (CN)
- Children's Hospital of Zhejiang University (CN)
- Wuhan Children's Hospital (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
- Yiwu Science and Technology Research Institute (CN)
- Fourth Affiliated Hospital of Anhui Medical University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2026-02-18
- DOI
- https://doi.org/10.1111/dom.70564
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00