Higher frequency of circulating regulatory T cells is associated with poor outcomes in patients with colorectal cancer

cTreg, cTfh, and cTfr levels are elevated in patients with CRC. An elevated cTreg frequency is associated with poor CRC prognosis. Assessment of cTreg levels may aid in prognostic assessment.

Authors

Longyi Zhang (ORCID: https://orcid.org/0000-0003-3625-489X)
Taotao Guo
Xinling PAN
Haoyang Guo
Yan Lu

Institutions

Wenzhou Medical University (CN)
Dongyang People's Hospital (CN)

Publication Details

Journal: Discover Oncology
Published: 2026-02-18
DOI: https://doi.org/10.1007/s12672-026-04710-0
Primary Topic: T-cell and B-cell Immunology
Type: article
Field-Weighted Citation Impact: 0.00

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article

Higher frequency of circulating regulatory T cells is associated with poor outcomes in patients with colorectal cancer

Longyi Zhang, Taotao Guo, Xinling PAN, Haoyang Guo et al.

Feb 18, 2026

Discover Oncology

T-cell and B-cell Immunology

article

Higher frequency of circulating regulatory T cells is associated with poor outcomes in patients with colorectal cancer

Longyi Zhang, Taotao Guo, Xinling PAN, Haoyang Guo, Yan Lu

February 18, 2026article en

Abstract

cTreg, cTfh, and cTfr levels are elevated in patients with CRC. An elevated cTreg frequency is associated with poor CRC prognosis. Assessment of cTreg levels may aid in prognostic assessment.

Discover OncologyVol. 17(1)

Wenzhou Medical University (CN), Dongyang People's Hospital (CN)

No poverty

Openalex Percentile: Top 49%

T-cell and B-cell Immunology

DOI Open Access PDF OpenAlex

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Higher frequency of circulating regulatory T cells is associated with poor outcomes in patients with colorectal cancer — Longyi Zhang, Taotao Guo, et al. · Discover Oncology (2026) | TGRS Research Map | TGRS