Analyses of the Coexpression of Lactate Metabolism- and Ferroptosis-Related Genes in Hepatocellular Carcinoma
An interplay exists between lactate metabolism and ferroptosis pathways in HCC, and the constructed risk model demonstrates predictive value for patient prognosis. As a critical gene, TRMU promotes HCC progression and suppresses ferroptosis through its high expression, suggesting it serves as a potential therapeutic target for HCC treatment.
Authors
- Qiao Chu (ORCID: https://orcid.org/0000-0001-7491-310X)
- Gao Cheng (ORCID: https://orcid.org/0009-0007-7583-7867)
- Kangjian Wu
- Decai Yu
- Shaolong Pei
- Tianming Chen
- Sheng Wang
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
- Nanjing Drum Tower Hospital (CN)
- Nanjing Jiangning Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Journal of Hepatocellular Carcinoma
- Published
- 2026-02-01
- DOI
- https://doi.org/10.2147/jhc.s569095
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00