SpectraNet: a novel model for polyp segmentation leveraging a spectral-guided mixture of functional experts

Automated and precise polyp segmentation from colonoscopy images is critical for the early diagnosis of colorectal cancer. However, this task is challenged by the ambiguous and low-contrast boundaries of polyps, which often blend with the surrounding mucosa. To address this, we propose SpectraNet, a novel hybrid-domain enhancement network for high-precision polyp segmentation. Our model is built on an encoder-decoder architecture with two core innovations integrated into its skip connections: (1) a Spectral-Guided Boundary Enhancement (SGBE) module that operates in the frequency domain to recover and sharpen indistinct boundary information by enhancing the phase spectrum of features, and (2) a Function-Specialized Mixture-of-Experts (FS-MoE) module that adaptively refines features for diverse polyp morphologies using a set of heterogeneous, function-specific experts. Extensive experiments on our curated PolypSegDataset and two public benchmarks (Kvasir-SEG and CVC-ClinicDB) demonstrate that our method consistently outperforms a wide range of state-of-the-art models. SpectraNet achieves superior performance in key segmentation metrics, and produces qualitatively more accurate segmentation masks with precise boundary definitions.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-02-18
DOI
https://doi.org/10.3389/fonc.2026.1734345
Primary Topic
Colorectal Cancer Screening and Detection
Type
article
Field-Weighted Citation Impact
0.00
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article

SpectraNet: a novel model for polyp segmentation leveraging a spectral-guided mixture of functional experts

Jing Ling, Zhong Liu
Frontiers in Oncology
Colorectal Cancer Screening and Detection
article

SpectraNet: a novel model for polyp segmentation leveraging a spectral-guided mixture of functional experts

Jing Ling, Zhong Liu
article en

Abstract

Automated and precise polyp segmentation from colonoscopy images is critical for the early diagnosis of colorectal cancer. However, this task is challenged by the ambiguous and low-contrast boundaries of polyps, which often blend with the surrounding mucosa. To address this, we propose SpectraNet, a novel hybrid-domain enhancement network for high-precision polyp segmentation. Our model is built on an encoder-decoder architecture with two core innovations integrated into its skip connections: (1) a Spectral-Guided Boundary Enhancement (SGBE) module that operates in the frequency domain to recover and sharpen indistinct boundary information by enhancing the phase spectrum of features, and (2) a Function-Specialized Mixture-of-Experts (FS-MoE) module that adaptively refines features for diverse polyp morphologies using a set of heterogeneous, function-specific experts. Extensive experiments on our curated PolypSegDataset and two public benchmarks (Kvasir-SEG and CVC-ClinicDB) demonstrate that our method consistently outperforms a wide range of state-of-the-art models. SpectraNet achieves superior performance in key segmentation metrics, and produces qualitatively more accurate segmentation masks with precise boundary definitions.

Frontiers in OncologyVol. 16
Nanjing University of Chinese Medicine (CN), Jiangning District of Nanjing Chinese Medicine Hospital (CN)
Openalex Percentile: Top 49%
Colorectal Cancer Screening and Detection
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