Xanthophyll-Rich Extracts from Garcinia dulcis Pulp as Potential Anti-Hepatocellular Carcinoma Functional Food

Xanthophyll-rich extracts from <i>Garcinia dulcis</i> pulp exhibit potent and selective anti-hepatocellular carcinoma activity through multi-target mechanisms involving oncogenic signaling, apoptosis regulation, and tumor metabolism. These findings support the translational potential of <i>G. dulcis</i> xanthophylls as promising natural candidates for further development in HCC therapy.

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Publication Details

Journal
Nutrients
Published
2026-02-18
DOI
https://doi.org/10.3390/nu18040670
Primary Topic
Natural Compound Pharmacology Studies
Type
article
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Xanthophyll-Rich Extracts from Garcinia dulcis Pulp as Potential Anti-Hepatocellular Carcinoma Functional Food

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Xanthophyll-Rich Extracts from Garcinia dulcis Pulp as Potential Anti-Hepatocellular Carcinoma Functional Food

Amal Arifi Hidayat, Ugroseno Yudho Bintoro, Muhammad Zulfikar Fiko Defianto, Aryati Aryati, Aji Bayu Wicaksono, Ulfa Kholili, Soetjipto Soetjipto
article en

Abstract

Xanthophyll-rich extracts from <i>Garcinia dulcis</i> pulp exhibit potent and selective anti-hepatocellular carcinoma activity through multi-target mechanisms involving oncogenic signaling, apoptosis regulation, and tumor metabolism. These findings support the translational potential of <i>G. dulcis</i> xanthophylls as promising natural candidates for further development in HCC therapy.

NutrientsVol. 18(4)
Universitas Airlangga (ID), Universitas Dr. Soetomo (ID)
Good health and well-being
Openalex Percentile: Top 51%
Natural Compound Pharmacology Studies
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