ACSA2 is not astrocyte-specific: implications for cell sorting strategies in the rodent brain
These findings caution against the usage of ACSA2 for astrocyte purification without exclusion markers to achieve high-purity astrocyte populations for downstream multi-omics analyses.
Authors
- Boyan K. Tsankov (ORCID: https://orcid.org/0000-0002-6525-5173)
- Gabriel Khelifi (ORCID: https://orcid.org/0000-0002-8973-7345)
- E Daniele (ORCID: https://orcid.org/0000-0002-2189-4678)
- Chiara Beretta (ORCID: https://orcid.org/0000-0002-9554-315X)
- Samer M. I. Hussein (ORCID: https://orcid.org/0000-0002-8504-3370)
- Maryam Faiz
- D J Philpott
- Daniel Beretta
- K. W. Annie Bang
Institutions
- Allen Institute for Brain Science (US)
- University of Calgary (CA)
- University of Toronto (CA)
- Lunenfeld-Tanenbaum Research Institute (CA)
- Alberta Children's Hospital (CA)
- Centre hospitalier de l'Université Laval (CA)
- Université Laval (CA)
- Hotchkiss Brain Institute (CA)
Publication Details
- Journal
- Frontiers in Cellular Neuroscience
- Published
- 2026-02-18
- DOI
- https://doi.org/10.3389/fncel.2026.1756677
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Canadian Institutes of Health Research
- Natural Sciences and Engineering Research Council of Canada
- Fonds de Recherche du Québec - Santé