Temporal variability of urinary microcystin-LR concentrations in healthy adult men: Recommendations for sampling strategy

Our study suggests that predicting an individual's long-term average MC-LR exposure level from a single spot urine sample is likely to result in misclassification of exposure. Collecting two or more urine samples from individuals at different time points substantially improves exposure assessment accuracy.

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Publication Details

Journal
Journal of Advanced Research
Published
2026-02-01
DOI
https://doi.org/10.1016/j.jare.2026.02.017
Primary Topic
Aquatic Ecosystems and Phytoplankton Dynamics
Type
article
Field-Weighted Citation Impact
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article

Temporal variability of urinary microcystin-LR concentrations in healthy adult men: Recommendations for sampling strategy

Xingde Du, X D Liu, Fufang Wang, Jialiang Hou et al.
Journal of Advanced Research
Aquatic Ecosystems and Phytoplankton Dynamics
article

Temporal variability of urinary microcystin-LR concentrations in healthy adult men: Recommendations for sampling strategy

Xingde Du, X D Liu, Fufang Wang, Jialiang Hou, Hailong Zhang, Wei Yang, Feiyang Guo, Xinghai Chen, Kangfeng Ge, Xiang Ji, Ruiyang Meng, Haibin Guo, Jun Yang, Xiao Liang, Shuo Zhao, Wenqian Huo, Yu Fu, Pengle Pang, Hao Wu
article en

Abstract

Our study suggests that predicting an individual's long-term average MC-LR exposure level from a single spot urine sample is likely to result in misclassification of exposure. Collecting two or more urine samples from individuals at different time points substantially improves exposure assessment accuracy.

Journal of Advanced Research
St. Mary's University, Texas (US), Zhengzhou University (CN), Henan Provincial People's Hospital (CN), First Affiliated Hospital of Zhengzhou University (CN), Beijing Center for Disease Prevention and Control (CN), Zhengzhou University of Industrial Technology (CN), Weifang University (CN)
Zero hunger
Openalex Percentile: Top 56%
Aquatic Ecosystems and Phytoplankton Dynamics
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