Exploring the anti-fibrotic effects of safflower in systemic sclerosis based on metabolomics and gut microbiota analyses
Safflower alleviated fibrotic and inflammatory phenotypes in systemic sclerosis, which may be associated with the modulation of gut microbiota composition and metabolic homeostasis.
Authors
- Yi Huang (ORCID: https://orcid.org/0000-0002-2867-1477)
- Ping Xie (ORCID: https://orcid.org/0000-0001-5878-087X)
- Kai Li (ORCID: https://orcid.org/0009-0000-1052-0710)
- Yalin Zhang (ORCID: https://orcid.org/0000-0001-8955-8139)
- Junying Lv
- Xueyan Zhou
- Chao Wang
Institutions
- Guangxi Medical University (CN)
- The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-02-18
- DOI
- https://doi.org/10.3389/fphar.2026.1719219
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00