Development and internal validation of a TLR2-based nomogram for diagnosing pulmonary infection in type 2 diabetes

TLR2, IL-6, TNF-α, ESR, age, and duration of diabetes can serve as a combined biomarker panel to aid in the early diagnosis of pulmonary infection in T2DM patients at hospital admission. The proposed nomogram demonstrates strong diagnostic performance and potential clinical utility.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-02-18
DOI
https://doi.org/10.3389/fendo.2026.1764904
Primary Topic
Immune Response and Inflammation
Type
article
Field-Weighted Citation Impact
0.00
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article

Development and internal validation of a TLR2-based nomogram for diagnosing pulmonary infection in type 2 diabetes

Yingjie Ma, Fufang Qin
Frontiers in Endocrinology
Immune Response and Inflammation
article

Development and internal validation of a TLR2-based nomogram for diagnosing pulmonary infection in type 2 diabetes

Yingjie Ma, Fufang Qin
article en

Abstract

TLR2, IL-6, TNF-α, ESR, age, and duration of diabetes can serve as a combined biomarker panel to aid in the early diagnosis of pulmonary infection in T2DM patients at hospital admission. The proposed nomogram demonstrates strong diagnostic performance and potential clinical utility.

Frontiers in EndocrinologyVol. 17
Henan University of Traditional Chinese Medicine (CN), Fifth Affiliated Hospital of Zhengzhou University (CN)
Reduced inequalities
Openalex Percentile: Top 50%
Immune Response and Inflammation
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