Effect of Dentin Biomodification on the Survival of Resin Composite Restorations: An Umbrella Review

Systematically identifying and characterizing dentin biomodifiers within their limitations lays the groundwork for evidence-based frameworks that guide dentists and shape future research. At present, physical scrubbing and air abrasion are the only readily available dentin biomodification techniques. Riboflavin and chitosan show promise as effective natural and affordable agents; however, their clinical use needs regulatory approval. In contrast, NaOCl should be avoided as it compromises composite restoration's durability.