Tirzepatide on physical function in adults with overweight or obesity: A systematic review and meta‐analysis
Tirzepatide 10 and 15 mg once weekly significantly improve patient-reported physical function in adults with overweight or obesity. These findings suggest tirzepatide enhances perceived physical capacity and quality of life, although the extremely high between-study heterogeneity limits the interpretability of pooled estimates and warrants cautious interpretation.
Authors
- Marcelo Fernando Ronsoni (ORCID: https://orcid.org/0000-0003-1187-9842)
- Letícia Machado (ORCID: https://orcid.org/0000-0002-6969-2813)
- Bruno C. dos Santos (ORCID: https://orcid.org/0000-0001-7814-5945)
- P Schmidt (ORCID: https://orcid.org/0000-0002-4348-3319)
- João Victor Ramos da Cruz
- Simone van de Sande‐Lee
- Lis Sodré Nonato de Souza
- Vitor Sodré Nonato de Souza
- João Vitor Ahlf Rodrigues
- Alexandre Hohl
Institutions
- Universidade Federal de Ciências da Saúde de Porto Alegre (BR)
- Universidade Federal de Santa Catarina (BR)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2026-02-18
- DOI
- https://doi.org/10.1111/dom.70529
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Eli Lilly and Company
- Novo Nordisk
- Servier
- Daiichi Sankyo Europe