Joint and Independent Associations of Gestational Diabetes and Depression With Childhood Obesity

In this cohort study, both prenatal depression and gestational diabetes were associated with childhood obesity risk, with larger effect sizes observed for gestational diabetes. Children exposed to both conditions had the greatest risk, although associations appeared additive rather than synergistic. These findings underscore the need for universal prenatal screening and risk stratification, along with targeted interventions for children exposed to these conditions.

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Publication Details

Journal
JAMA Network Open
Published
2026-02-18
DOI
https://doi.org/10.1001/jamanetworkopen.2025.59344
Primary Topic
Gestational Diabetes Research and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Joint and Independent Associations of Gestational Diabetes and Depression With Childhood Obesity

Meggan E. Craft, Mara Greenberg, Amanda L. Ngo, Alicia Peterson et al.
JAMA Network Open
Gestational Diabetes Research and Management
article

Joint and Independent Associations of Gestational Diabetes and Depression With Childhood Obesity

Meggan E. Craft, Mara Greenberg, Amanda L. Ngo, Alicia Peterson, Yeyi Zhu, Assiamira Ferrara, Charles P. Quesenberry
article en

Abstract

In this cohort study, both prenatal depression and gestational diabetes were associated with childhood obesity risk, with larger effect sizes observed for gestational diabetes. Children exposed to both conditions had the greatest risk, although associations appeared additive rather than synergistic. These findings underscore the need for universal prenatal screening and risk stratification, along with targeted interventions for children exposed to these conditions.

JAMA Network OpenVol. 9(2)
Kaiser Permanente (US), Carestream (United States) (US), Kaiser Permanente Oakland Medical Center (US)
Good health and well-being
Openalex Percentile: Top 48%
Gestational Diabetes Research and Management
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