Managing a Pregnant Patient With a Mechanical Heart Valve and Subchorionic Hematomas

For high-risk pregnant patients with mechanical valves, modifying anticoagulation targets is a viable strategy to manage bleeding complications without stopping therapy. Titrating anticoagulation to a lower, yet still therapeutic, anti-Xa target can successfully balance the risk of bleeding with the need to prevent catastrophic valve thrombosis.

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Publication Details

Journal
JACC Case Reports
Published
2026-02-01
DOI
https://doi.org/10.1016/j.jaccas.2025.106549
Citations
1
Primary Topic
Cardiovascular Issues in Pregnancy
Type
article
Field-Weighted Citation Impact
30.07
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article

Managing a Pregnant Patient With a Mechanical Heart Valve and Subchorionic Hematomas

Jenica Thangathurai, Nare Torosyan, Shakeela Faulkner, Uri Elkayam
1 citations
JACC Case Reports
Cardiovascular Issues in Pregnancy
30.07
article

Managing a Pregnant Patient With a Mechanical Heart Valve and Subchorionic Hematomas

Jenica Thangathurai, Nare Torosyan, Shakeela Faulkner, Uri Elkayam
article en
1 citations

Abstract

For high-risk pregnant patients with mechanical valves, modifying anticoagulation targets is a viable strategy to manage bleeding complications without stopping therapy. Titrating anticoagulation to a lower, yet still therapeutic, anti-Xa target can successfully balance the risk of bleeding with the need to prevent catastrophic valve thrombosis.

JACC Case ReportsVol. 31(7)
University of Southern California (US)
Good health and well-being
Openalex Percentile: Top 1%
Cardiovascular Issues in Pregnancy
30.07
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