Linvoseltamab, a BCMA-directed CD3 T-cell engager for multiple myeloma: a patient-centric option via a response-adapted dosing regimen

Linvoseltamab is the fourth FDA approved bispecific antibody for the treatment of RRMM in patients who have received four or more lines of therapy. Cross-trial comparisons ave suggested that linvoseltamab has comparable to slightly better efficacy compared with other agents. Linvoseltamab offers an optimized dosing regimen with a favorable CRS profile. Further real-world data are needed to understand linvoseltamab's role within the MM treatment paradigm.

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Publication Details

Journal
Expert Review of Hematology
Published
2026-02-19
DOI
https://doi.org/10.1080/17474086.2026.2634283
Citations
1
Primary Topic
Multiple Myeloma Research and Treatments
Type
article
Field-Weighted Citation Impact
35.41
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article

Linvoseltamab, a BCMA-directed CD3 T-cell engager for multiple myeloma: a patient-centric option via a response-adapted dosing regimen

Mohammad Rattu, Marina Samuel, J. Richter, Marcus Flores et al.
1 citations
Expert Review of Hematology
Multiple Myeloma Research and Treatments
35.41
article

Linvoseltamab, a BCMA-directed CD3 T-cell engager for multiple myeloma: a patient-centric option via a response-adapted dosing regimen

Mohammad Rattu, Marina Samuel, J. Richter, Marcus Flores, J. Lowy, Michael Rogers, Zachary M Avigan
article en
1 citations

Abstract

Linvoseltamab is the fourth FDA approved bispecific antibody for the treatment of RRMM in patients who have received four or more lines of therapy. Cross-trial comparisons ave suggested that linvoseltamab has comparable to slightly better efficacy compared with other agents. Linvoseltamab offers an optimized dosing regimen with a favorable CRS profile. Further real-world data are needed to understand linvoseltamab's role within the MM treatment paradigm.

Expert Review of Hematology
Icahn School of Medicine at Mount Sinai (US)
Good health and well-being
Openalex Percentile: Top 1%
Multiple Myeloma Research and Treatments
35.41
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