Linvoseltamab, a BCMA-directed CD3 T-cell engager for multiple myeloma: a patient-centric option via a response-adapted dosing regimen
Linvoseltamab is the fourth FDA approved bispecific antibody for the treatment of RRMM in patients who have received four or more lines of therapy. Cross-trial comparisons ave suggested that linvoseltamab has comparable to slightly better efficacy compared with other agents. Linvoseltamab offers an optimized dosing regimen with a favorable CRS profile. Further real-world data are needed to understand linvoseltamab's role within the MM treatment paradigm.
Authors
- Mohammad Rattu (ORCID: https://orcid.org/0009-0009-2939-4385)
- Marina Samuel
- J. Richter
- Marcus Flores
- J. Lowy
- Michael Rogers
- Zachary M Avigan
Institutions
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Expert Review of Hematology
- Published
- 2026-02-19
- DOI
- https://doi.org/10.1080/17474086.2026.2634283
- Citations
- 1
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 35.41