In transected nerves, distal repair Schwann cells are required at the injury site to direct and accelerate axonal regrowth
After nerve transection in larval zebrafish, proximal and distal Schwann cells have distinct functions at injury siteA single distal repair Schwann cell is sufficient for axonal regrowthAxonal regrowth is normal in mutants without macrophages.
Authors
- William S. Talbot (ORCID: https://orcid.org/0000-0002-2048-7472)
- Daniel Elliott Lysko
- Annika R Johnson
Institutions
- Stanford University (US)
Publication Details
- Journal
- bioRxiv (Cold Spring Harbor Laboratory)
- Published
- 2026-02-18
- DOI
- https://doi.org/10.64898/2026.02.17.706483
- Primary Topic
- Nerve injury and regeneration
- Type
- article
- Field-Weighted Citation Impact
- 0.00