Papillary carcinoma in thyroglossal duct cyst: A case report

Thyroglossal duct cyst malignancies are rare phenomena which usually present as midline swelling. Ultrasonography and computed tomography show solid-cystic components, irregular margins and calcifications. Fine needle aspiration cytology is inconclusive and diagnosis is confirmed by histopathological analysis. We present a case of 36 year old female who presented with painless midline swelling. On ultrasonography and contrast enhanced computed tomography, solid-cystic lesion with few foci of calcifications was noted. Involvement of strap muscles was determined by computed tomography. Fine Needle Aspiration Cytology showed papillary carcinoma which was further proven by histopathological analysis after surgery.

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Journal
Radiology Case Reports
Published
2026-02-18
DOI
https://doi.org/10.1016/j.radcr.2026.01.075
Primary Topic
Head and Neck Anomalies
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article
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article

Papillary carcinoma in thyroglossal duct cyst: A case report

Abhishek Pandey, Sabina Rijal, Aayushma Shrestha, Saugat Karki
Radiology Case Reports
Head and Neck Anomalies
article

Papillary carcinoma in thyroglossal duct cyst: A case report

Abhishek Pandey, Sabina Rijal, Aayushma Shrestha, Saugat Karki
article en

Abstract

Thyroglossal duct cyst malignancies are rare phenomena which usually present as midline swelling. Ultrasonography and computed tomography show solid-cystic components, irregular margins and calcifications. Fine needle aspiration cytology is inconclusive and diagnosis is confirmed by histopathological analysis. We present a case of 36 year old female who presented with painless midline swelling. On ultrasonography and contrast enhanced computed tomography, solid-cystic lesion with few foci of calcifications was noted. Involvement of strap muscles was determined by computed tomography. Fine Needle Aspiration Cytology showed papillary carcinoma which was further proven by histopathological analysis after surgery.

Radiology Case ReportsVol. 21(5)
Nepal Medical College Teaching Hospital (NP), Bir Hospital (NP), Biratnagar Eye Hospital (NP), Himalayan Rescue Association (NP)
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Openalex Percentile: Top 51%
Head and Neck Anomalies
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Papillary carcinoma in thyroglossal duct cyst: A case report — Abhishek Pandey, Sabina Rijal, et al. · Radiology Case Reports (2026) | TGRS Research Map | TGRS