Intense Pulsed Light for Perennial Allergic Conjunctivitis: A Prospective Interventional Study with Untargeted Tear Metabolomics

An IPL-augmented regimen may alleviate moderate-to-severe PAC, which is consistent with the modulation of purine and unsaturated fatty acid metabolism. This modulation is characterized by suppressed purine activity and proinflammatory lipids while enhancing anti-inflammatory and antioxidant unsaturated fatty acids. These changes collectively dampen inflammation and promote immune homeostasis.

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Publication Details

Journal
Photobiomodulation Photomedicine and Laser Surgery
Published
2026-02-01
DOI
https://doi.org/10.1177/25785478251411050
Primary Topic
Ocular Surface and Contact Lens
Type
article
Field-Weighted Citation Impact
0.00
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article

Intense Pulsed Light for Perennial Allergic Conjunctivitis: A Prospective Interventional Study with Untargeted Tear Metabolomics

Qiu Ji Yan, Dan Li
Photobiomodulation Photomedicine and Laser Surgery
Ocular Surface and Contact Lens
article

Intense Pulsed Light for Perennial Allergic Conjunctivitis: A Prospective Interventional Study with Untargeted Tear Metabolomics

Qiu Ji Yan, Dan Li
article en

Abstract

An IPL-augmented regimen may alleviate moderate-to-severe PAC, which is consistent with the modulation of purine and unsaturated fatty acid metabolism. This modulation is characterized by suppressed purine activity and proinflammatory lipids while enhancing anti-inflammatory and antioxidant unsaturated fatty acids. These changes collectively dampen inflammation and promote immune homeostasis.

Photobiomodulation Photomedicine and Laser SurgeryVol. 44(2)
Chinese University of Hong Kong (HK), Shantou University (CN)
Good health and well-being
Openalex Percentile: Top 54%
Ocular Surface and Contact Lens
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Intense Pulsed Light for Perennial Allergic Conjunctivitis: A Prospective Interventional Study with Untargeted Tear Metabolomics — Qiu Ji Yan, Dan Li · Photobiomodulation Photomedicine and Laser Surgery (2026) | TGRS Research Map | TGRS