Advances in Hyperbaric Oxygen Therapy: Medical Benefits and Technical Perspectives

In the rapidly evolving landscape of medicine, hyperbaric oxygen therapy (HBOT) has emerged as a clinically recognized treatment involving the inhalation of pure oxygen in a pressurized chamber. Despite its proven applications, further research is needed to understand and simulate the physical processes governing HBOT. This paper presents a novel modeling technique and an automated pressurized chamber specifically designed for laboratory studies to better analyze oxygenated air circulation in hyperbaric environments. The proposed model integrates hydraulic principles and geometric constraints to replicate real-world HBOT dynamics. It incorporates dimensionless equations, including Reynolds, Froude, and Archimedes principles, to account for fluid motion, energy dissipation, and pressure field behavior. Geometric conditions involve initial and boundary parameters such as velocity, temperature, pressure, concentration, and mass density. For realistic simulation, both physical and geometric similarity conditions must be satisfied. To enhance the generalizability of results, the Ruark transformation is employed to introduce dimensionless coordinates, allowing findings to extend to related scenarios.The proposed laboratory model demonstrates the ability to accurately simulate complex oxygenation and flow dynamics in pressurized environments. The automated chamber ensures precise control and experimental reproducibility. The model effectively reproduces velocity fields and pressure distributions across varied geometric and dynamic configurations.By combining hydraulic theory with geometric modeling, this study provides a robust framework for exploring HBOT mechanisms in a controlled setting. The approach not only advances theoretical understanding but also lays the groundwork for future experimental and clinical investigations in hyperbaric therapy and similar therapeutic environments.

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Publication Details

Journal
Annals of Biomedical Engineering
Published
2026-02-18
DOI
https://doi.org/10.1007/s10439-026-04027-7
Primary Topic
Intravenous Infusion Technology and Safety
Type
article
Field-Weighted Citation Impact
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article

Advances in Hyperbaric Oxygen Therapy: Medical Benefits and Technical Perspectives

Marius Popescu, Monica Ciobanu, Antoanela Naaji
Annals of Biomedical Engineering
Intravenous Infusion Technology and Safety
article

Advances in Hyperbaric Oxygen Therapy: Medical Benefits and Technical Perspectives

Marius Popescu, Monica Ciobanu, Antoanela Naaji
article en

Abstract

In the rapidly evolving landscape of medicine, hyperbaric oxygen therapy (HBOT) has emerged as a clinically recognized treatment involving the inhalation of pure oxygen in a pressurized chamber. Despite its proven applications, further research is needed to understand and simulate the physical processes governing HBOT. This paper presents a novel modeling technique and an automated pressurized chamber specifically designed for laboratory studies to better analyze oxygenated air circulation in hyperbaric environments. The proposed model integrates hydraulic principles and geometric constraints to replicate real-world HBOT dynamics. It incorporates dimensionless equations, including Reynolds, Froude, and Archimedes principles, to account for fluid motion, energy dissipation, and pressure field behavior. Geometric conditions involve initial and boundary parameters such as velocity, temperature, pressure, concentration, and mass density. For realistic simulation, both physical and geometric similarity conditions must be satisfied. To enhance the generalizability of results, the Ruark transformation is employed to introduce dimensionless coordinates, allowing findings to extend to related scenarios.The proposed laboratory model demonstrates the ability to accurately simulate complex oxygenation and flow dynamics in pressurized environments. The automated chamber ensures precise control and experimental reproducibility. The model effectively reproduces velocity fields and pressure distributions across varied geometric and dynamic configurations.By combining hydraulic theory with geometric modeling, this study provides a robust framework for exploring HBOT mechanisms in a controlled setting. The approach not only advances theoretical understanding but also lays the groundwork for future experimental and clinical investigations in hyperbaric therapy and similar therapeutic environments.

Annals of Biomedical Engineering
Vasile Goldis Western University of Arad (RO)
Openalex Percentile: Top 52%
Intravenous Infusion Technology and Safety
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