The Critical Care Phenotype of Hypokalemic Paralysis: Etiology, Outcomes, and Predictors of Respiratory Failure in a Retrospective Cohort Study

HPP in the ICU represents a distinct critical care phenotype with a high risk of respiratory failure. As the requirement for mechanical ventilation was not predicted by admission potassium levels, vigilant monitoring for respiratory muscle fatigue is warranted in all cases. Favorable outcomes are achievable with prompt correction and treatment of the underlying cause, reinforcing that HPP is a reversible ICU emergency.

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Publication Details

Journal
Cureus
Published
2026-02-18
DOI
https://doi.org/10.7759/cureus.103865
Primary Topic
Ion channel regulation and function
Type
article
Field-Weighted Citation Impact
0.00
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article

The Critical Care Phenotype of Hypokalemic Paralysis: Etiology, Outcomes, and Predictors of Respiratory Failure in a Retrospective Cohort Study

Abhishek Srivastava, Arunkumar R Pande, Ashish Awasthi, Nitin Rai et al.
Cureus
Ion channel regulation and function
article

The Critical Care Phenotype of Hypokalemic Paralysis: Etiology, Outcomes, and Predictors of Respiratory Failure in a Retrospective Cohort Study

Abhishek Srivastava, Arunkumar R Pande, Ashish Awasthi, Nitin Rai, Indu C Srivastava, Sandeep Agarwal, Shilpi Manchanda
article en

Abstract

HPP in the ICU represents a distinct critical care phenotype with a high risk of respiratory failure. As the requirement for mechanical ventilation was not predicted by admission potassium levels, vigilant monitoring for respiratory muscle fatigue is warranted in all cases. Favorable outcomes are achievable with prompt correction and treatment of the underlying cause, reinforcing that HPP is a reversible ICU emergency.

CureusVol. 18(2)
Central Drug Research Institute (IN), University of Lucknow (IN)
Good health and well-being
Openalex Percentile: Top 51%
Ion channel regulation and function
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