High‐Dose Continuous Infusion Ifosfamide as Effective Palliation in a Patient With Relapsed Ewing Sarcoma With Bone Marrow Infiltration and Severe Thrombocytopenia: A Case Report
To our knowledge, this is the first described case of a patient with bone marrow infiltration from Ewing sarcoma presenting with severe thrombocytopenia successfully managed with low-dose continuous infusion ifosfamide, providing almost 7 months of progression-free survival. Considering the very dismal prognosis of Ewing sarcoma relapsing with bone marrow infiltration, this case might be of help when decision-making is required in this setting.
Authors
- Ilaria Tortorelli (ORCID: https://orcid.org/0000-0002-6331-4096)
- M. Sbaraglia
- A. Galiano
- Fabio Murtas (ORCID: https://orcid.org/0009-0009-7617-916X)
- Benedetta Chiusole (ORCID: https://orcid.org/0000-0001-6449-6402)
- Silvia Finotto
- Maital Bolshinsky (ORCID: https://orcid.org/0000-0001-6380-1321)
- Elena Bellan (ORCID: https://orcid.org/0000-0003-3294-6055)
- Antonella Brunello
- Marina Coppola
- A. Dei Tos
- Marta Burei
Institutions
- University of Padua (IT)
- Istituto Oncologico Veneto (IT)
Publication Details
- Journal
- Cancer Reports
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/cnr2.70468
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministero della Salute