Effect of transplanted oligodendrocyte precursor cells derived from inflammatory and non-inflammatory microenvironment on remyelination in a chronic cuprizone model

OPC transplantation improves remyelination and reduces the CSPG level, but the effectiveness is more related to the previous history of the OPC isolation microenvironment and the new donor.

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Publication Details

Journal
PLoS ONE
Published
2026-02-18
DOI
https://doi.org/10.1371/journal.pone.0343039
Primary Topic
Neurogenesis and neuroplasticity mechanisms
Type
article
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0.00
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article

Effect of transplanted oligodendrocyte precursor cells derived from inflammatory and non-inflammatory microenvironment on remyelination in a chronic cuprizone model

Iraj Ragerdi-Kashani, Parichehr Pasbakhsh, Farzaneh Rezaei-Yazdi, Hoda Akbari
PLoS ONE
Neurogenesis and neuroplasticity mechanisms
article

Effect of transplanted oligodendrocyte precursor cells derived from inflammatory and non-inflammatory microenvironment on remyelination in a chronic cuprizone model

Iraj Ragerdi-Kashani, Parichehr Pasbakhsh, Farzaneh Rezaei-Yazdi, Hoda Akbari
article en

Abstract

OPC transplantation improves remyelination and reduces the CSPG level, but the effectiveness is more related to the previous history of the OPC isolation microenvironment and the new donor.

PLoS ONEVol. 21(2)
Tehran University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 61%
Neurogenesis and neuroplasticity mechanisms
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Effect of transplanted oligodendrocyte precursor cells derived from inflammatory and non-inflammatory microenvironment on remyelination in a chronic cuprizone model — Iraj Ragerdi-Kashani, Parichehr Pasbakhsh, et al. · PLoS ONE (2026) | TGRS Research Map | TGRS