GP IIb/IIIa platelet receptor inhibitor for acute stent thrombosis with technically impossible percutaneous intervention

Over the past 10—15 years, more than ten blockers of GP IIb/IIIa platelet receptors have been created. Mechanism of their action is blockade of membrane glycoprotein receptors of platelets that leads to suppression of common final pathway of aggregation. GP IIb/IIIa platelet receptor inhibitor eliminated coronary artery thrombosis according to coronary angiography and allowed restoration of coronary blood flow in “no-reflow” phenomenon in 100% of cases. The authors used GP IIb/IIIa inhibitor of platelet receptors for the treatment of acute stent thrombosis with technical impossibility of repeated percutaneous coronary intervention with positive effect.

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Publication Details

Journal
Russian Journal of Cardiology and Cardiovascular Surgery
Published
2026-02-18
DOI
https://doi.org/10.17116/kardio202619011117
Primary Topic
Platelet Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

GP IIb/IIIa platelet receptor inhibitor for acute stent thrombosis with technically impossible percutaneous intervention

В. И. Ганюков, A.I. Danilovich, R.S. Tarasov
Russian Journal of Cardiology and Cardiovascular Surgery
Platelet Disorders and Treatments
article

GP IIb/IIIa platelet receptor inhibitor for acute stent thrombosis with technically impossible percutaneous intervention

В. И. Ганюков, A.I. Danilovich, R.S. Tarasov
article en

Abstract

Over the past 10—15 years, more than ten blockers of GP IIb/IIIa platelet receptors have been created. Mechanism of their action is blockade of membrane glycoprotein receptors of platelets that leads to suppression of common final pathway of aggregation. GP IIb/IIIa platelet receptor inhibitor eliminated coronary artery thrombosis according to coronary angiography and allowed restoration of coronary blood flow in “no-reflow” phenomenon in 100% of cases. The authors used GP IIb/IIIa inhibitor of platelet receptors for the treatment of acute stent thrombosis with technical impossibility of repeated percutaneous coronary intervention with positive effect.

Russian Journal of Cardiology and Cardiovascular SurgeryVol. 19(1)
Kemerovo State University (RU)
Openalex Percentile: Top 50%
Platelet Disorders and Treatments
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