Abuse history as a modifier of symptom phenotype in endometriosis: Insights from a multidimensional retrospective cohort

A combined history of endometriosis and abuse was associated with a high symptom burden characterized by pain amplification, GI distress, and central sensitization. These findings underscore the importance of early psychosocial screening and trauma-informed care as complements to biomedical management in endometriosis. Prospective studies incorporating validated trauma measures and treatment covariates are warranted to clarify mechanisms and inform multidisciplinary care.