Hepatic and abdominal adiposity in type 2 diabetes as assessed with machine learning on computed tomography scans
Hepatic steatosis, hepatomegaly and visceral adiposity on CT are associated with type 2 diabetes. Hepatic changes may influence spleen size effects on diabetes. VSR can serve as an alternative to traditional obesity metrics to accurately reflect diabetes risk.
Authors
- James Gee
- Matthew T. MacLean (ORCID: https://orcid.org/0000-0002-0514-7218)
- Hersh Sagreiya
- P. Raghupathy (ORCID: https://orcid.org/0009-0000-6547-247X)
- Charles E. Kahn (ORCID: https://orcid.org/0000-0002-6654-7434)
- Abhijit Bhattaru (ORCID: https://orcid.org/0000-0002-1383-1992)
- Mohamad Hazim
- Richard H. Tran (ORCID: https://orcid.org/0009-0005-1466-9252)
- Sophia Swago
- Arijitt Borthakur
- Elizabeth Thompson
- Daniel J. Rader
- Jeffrey T. Duda
Institutions
- University of Massachusetts Chan Medical School (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2026-02-18
- DOI
- https://doi.org/10.1111/dom.70557
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Pennsylvania
- Institute for Translational Medicine and Therapeutics
- Sarnoff Cardiovascular Research Foundation
- University of Pennsylvania Health System
- National Institutes of Health
- National Heart, Lung, and Blood Institute
- NIH Office of the Director
- National Center for Advancing Translational Sciences