Oxaliplatin induced peripheral neuropathy and associated factors among colorectal cancer patients in Tanzania

The prevalence of acute and chronic OIPN among colorectal cancer patients managed at ORCI was 71.0% and 59.7% respectively, with most patients developing grade 1 and 2 neuropathy for both acute and chronic symptoms. Number of cycles, cumulative dose and BMI were the major factors associated with the neuropathy.

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Publication Details

Journal
BMC Cancer
Published
2026-02-18
DOI
https://doi.org/10.1186/s12885-026-15769-x
Primary Topic
Cancer Treatment and Pharmacology
Type
article
Field-Weighted Citation Impact
0.00
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article

Oxaliplatin induced peripheral neuropathy and associated factors among colorectal cancer patients in Tanzania

Nazima Dharsee, Emmanuel Mduma, Khamza Maunda, Mohamed Salat Gonjobe
BMC Cancer
Cancer Treatment and Pharmacology
article

Oxaliplatin induced peripheral neuropathy and associated factors among colorectal cancer patients in Tanzania

Nazima Dharsee, Emmanuel Mduma, Khamza Maunda, Mohamed Salat Gonjobe
article en

Abstract

The prevalence of acute and chronic OIPN among colorectal cancer patients managed at ORCI was 71.0% and 59.7% respectively, with most patients developing grade 1 and 2 neuropathy for both acute and chronic symptoms. Number of cycles, cumulative dose and BMI were the major factors associated with the neuropathy.

BMC CancerVol. 26(1)
Muhimbili University of Health and Allied Sciences (TZ), Muhimbili National Hospital (TZ), Ocean Road Cancer Institute (TZ)
Openalex Percentile: Top 50%
Cancer Treatment and Pharmacology
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Oxaliplatin induced peripheral neuropathy and associated factors among colorectal cancer patients in Tanzania — Nazima Dharsee, Emmanuel Mduma, et al. · BMC Cancer (2026) | TGRS Research Map | TGRS